Research
Principal investigators of the Cologne Graduate School of Ageing Research (CGA) are internationally recognized scientists known for their cutting edge research into diverse topics including genetic determinants of longevity, protein quality control, DNA damage and repair, mitochondria regulation, immunosenescence and inflammation, stem cell and tissue maintenance, organellar and cellular architecture, endocrine control of metabolism, as well as their research into age-related diseases such as neurodegeneration, cancer, diabetes, obesity, kidney dysfunction. Close links between the research groups foster interdisciplinary collaboration and promote the development of novel research approaches.
The laboratories use diverse model systems - from bacteria, yeast, worms, and flies, to fish, mice, cultured cells, and human clinical samples - to delve into basic mechanistic questions. Core facilities provide on-campus platforms for performing genomics, proteomics, lipidomics, imaging, cell sorting, metabolic profiling and phenotyping.
A list of available laboratories for the current call can be found here.
* Most principal investigators own multiple affiliations, only the main affiliations of the CGA partner institutes being mentioned here. Further affiliations can be found e.g. here.
Principal Investigators and their Research Areas *
Prof. Dr. Adam Antebi
Director MPI for Biology of Ageing
Molecular Genetics of Ageing
Antebi Lab
Prof. Dr. Thomas Benzing
CECAD Principal Investigator
Kidney Research
Nephrolab
Prof. Dr. Matteo Bergami
CECAD Principal Investigator
Mechanisms of Neuronal De- and Regeneration
Bergami Lab
Prof. Dr. Andreas Beyer
CECAD Principal Investigator
Cellular Networks and Systems Biology
Beyer Lab
Prof. Dr. Jens Brüning
Director of MPI for Metabolism Research
Neuronal Control of Metabolism and Ageing
Brüning Lab
PROF. DR. Filipe Cabreiro
CECAD Principal Investigator
Microbiome and Ageing
Cabreiro Lab
Prof. Dr. Oliver Cornely
CECAD Principal Investigator and Leader Translational Platform
Translation of clinical research findings into practical applications
Cornely Lab
Dr. Mauro Corrado
CECAD Principal Investigator
Study of cardiolipin synthesis and remodelling in immunity and inflammation
Corrado Lab
Dr. Joris Deelen
MPI for Biology of Ageing Principal Investigator
Genetics and Biomarkers of Human Ageing
Deelen Lab
Dr. Constantinos Demetriades
MPI for Biology of Ageing Principal Investigator
Cell Growth control in Health and age-related Disease
Demetriades Lab
Dr. Martin Denzel
MPI for Biology of Ageing Principal Investigator
Metabolic and Genetic Regulation of Ageing
Denzel Lab
Prof. Dr. Irina Dudanova
CECAD Principal Investigator
Molecular Neurodegeneration
Dudanova Lab
Dr. Mafalda Escobar-Henriques
CECAD Principal Investigator
Mitochondrial Dynamics in Health and Disease
Escobar Lab
Dr. Henning Fenselau
MPI for Metabolism Research Principal Investigator
Synaptic Transmission in Energy Homeostasis
Fenselau Lab
Dr. Zak Frentz
MPI for Biology of Ageing
Systems Biology of Ageing
Frentz lab
Prof. Dr. Christian Frezza
CECAD Principal Investigator
Cancer Metabolism
Frezza lab
Prof. Dr. Ana J. Garcia-Saéz
CECAD Principal Investigator
Membrane Biophysics
Garcia-Saéz Lab
Prof. Dr. Thorsten Hoppe
CECAD Principal Investigator
Proteostasis in Development and Ageing
Hoppe Lab
Dr. Ina Huppertz
MPI for Biology of Ageing Principal Investigator
RNA-Binding Proteins in Metabolism and Ageing
Huppertz Lab
Dr. Ron Jachimowicz
MPI for Biology of Ageing Principal Investigator
Mechanisms of DNA Repair
Jachimowicz Lab
Dr. Christina Ising
CECAD Principal Investigator
Inflammation and cell death in Alzheimer's disease and other tauopathies
Ising Lab
Prof. Dr. Peter Kloppenburg
CECAD Principal Investigator
Analysis of Biophysical Parameters and Cellular Mechanisms Controlling Energy Homeostasis
Kloppenburg Lab
Prof. Dr. Tatiana Korotkova
CECAD Principal Investigator
Neuronal Circuits and Behaviour
Korotkova Lab
Prof. Dr. Thomas Langer
Director MPI for Biology of Ageing
Mitochondrial Proteostasis
Langer Lab
Dr. Ivan Matic
MPI for Biology of Ageing Principal Investigator
Proteomics of posttranslational Modifications
Matic Lab
Prof. Dr. Roman-Ulrich Müller
CECAD Principal Investigator
RNA-Biology in renal Damage and Cancer
Müller Lab
Prof. Dr. Carien Niessen
CECAD Scientific Coordinator and Principal Investigator
Cell Architecture in Tissue Homeostasis, Ageing and Disease
Niessen Lab
Dr. Stephanie Panier
MPI for Biology of Ageing Principal Investigator
Genome Instability and Ageing
Panier Lab
Prof. Manolis Pasparakis
CECAD Principal Investigator
Cell Death and Inflammation in Tissue Homeostasis and Disease
Pasparakis Lab
Dr. Lena Pernas
MPI for Biology of Ageing Principal Investigator
Metabolism of Infection
Pernas Lab
Dr. Jane Reznick
CECAD Principal Investigator
Metabolic adaptation in health and disease
Reznick Lab
Prof. Dr. Elena Rugarli
CECAD Principal Investigator
Pathogenic Mechanisms of Axonal Degeneration
Rugarli Lab
Prof. Dr. Björn Schumacher
CECAD Principal Investigator
DNA Damage and Ageing
Schumacher Lab
Prof. Dr. Anne Schaefer
Director MPI for Biology of Ageing
Neurobiology of Ageing
Schaefer lab
Dr. Hannah Scheiblich
MPI for Biology of Ageing Principal Investigator
Neuroimmunology of Ageing
Scheiblich Lab
Dr. Hans-Georg Sprenger
MPI for Biology of Ageing Principal Investigator
Molecular Metabolism & Energy Homeostasis
Sprenger Lab
Dr. Alessandra Stangherlin
CECAD Principal Investigator
Circadian Rhythms and Ion Homeostasis
Stangherlin Lab
Dr. Sophie Steculorum
MPI for Metabolism Research Principal Investigator
Neuronal Control of Brain Metabolism
Steculorum Lab
Dr. Lukas Steuernagel
MPI for Metabolism Research Principal Investigator
Neurogenomics
Steuernagel Lab
Dr. Gilles Storelli
CECAD Principal Investigator
Stress Signalism and Metabolism
Storelli Lab
Prof. Dr. Marc Tittgemeyer
MPI for Metabolism Research Principal Investigator
Neuronal Control of Metabolism, Human Neuroimaging, Translational & Computational Neuroscience
Tittgemeyer Lab
Prof. Dr. Achim Tresch
CECAD Principal Investigator
RNA metabolism, Epigenomics
Tresch Lab
Prof. Dr. Aleksandra Trifunovic
CECAD Principal Investigator
Understanding the Role of mitochondrial (Dys)Function in the Determination of Longevity
Trifunovic Lab
Prof. Dr. Mirka Uhlirova
CECAD Principal Investigator
Stress Signalling Development and Disease
Uhlirova Lab
Prof. Dr. David Vilchez
CECAD Principal Investigator
Proteostasis of Ageing and Stem Cells
Vilchez Lab
Prof. Dr. Silvia von Karstedt
CECAD Principal Investigator
Cell Death and Cancer Evolution
von Karstedt Lab
Prof. Dr. Henning Walczak
CECAD Principal Investigator
Cell Death and Inflammation
Walczak Lab
PD Dr. Thomas Wunderlich
MPI for Metabolism Research Principal Investigator
Mouse Genetics and Obesity-associated Cancer
Wunderlich Lab
Dr. Gabriele Zaffagnini
CECAD Principal Investigator
Protein Homeostasis during Female Reproduction and Reproductive Ageing