Strong Partners

The Cologne Graduate School of Ageing Research (CGA) in Germany is a joint venture of the University of Cologne Excellence Cluster on Stress Responses in Ageing-Associated Diseases (CECAD), the University Hospital Cologne, the Max Planck Institute for Biology of Ageing, the Max Planck Institute for Metabolism Research and the Center of Advanced European Studies and Research (caesar). Their close proximity maximizes opportunities for interaction and collaboration. The Cologne/Bonn area has emerged as a leading global research centre with a stellar constellation of institutes and scientists dedicated to ageing research in Life Sciences.

MPI for Biology of Ageing

Deciphering the mystery of ageing
Why do organisms age? How can we influence our life span? The overall goal of our research is to uncover the basic causes and processes of ageing. We also strive to understand the nature of longevity and age-related diseases. To do so, we aim to gain fundamental insights into the underlying molecular, physiological and evolutionary mechanisms. At the same time we investigate how the ageing process might be ameliorated with the longterm goal of increasing human health during ageing.
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Ageing – an unfavorable aspect of life?
The aim of the Cologne Cluster of Excellence in Cellular Stress Responses in Ageing-Associated Diseases is to understand the molecular mechanisms underlying the ageing process and thereby enable new therapies for ageing-associated diseases such as cancer, diabetes and neurodegenerative disorders to be developed. CECAD's interdisciplinary approach will reveal cross-over points between traditional research areas, and should help to identify common underlying causes for age-related diseases.
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MPI for Metabolism Research

The brain analyses nutrient-related and hormonal signals of the body periphery and controls not only the intake of energy but also coordinately regulates peripheral glucose metabolism. This central nervous control is complex and until now not fully understood. Research at the Max Planck Institute for Metabolism Research (formerly: Max Planck Institute for Neurological Research) is dedicated to deciphering these most intricate neuro-circuits. The researchers use modern technologies of neurocircuitry mapping in transgenic mice (optogenetics, DREADD) as well as multimodal and molecular imaging to describe the basics of intact but also abnormal metabolic regulation. Once neuronal signaling pathways of metabolism are completely understood not only in model organisms, but also in healthy people and patients, new molecular therapies for diseases such as type 2 diabetes and obesity may be developed in the long run.
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